Technician /Senior Technician in Protein Biochemistry, Zerial Group
Join to apply for the Technician /Senior Technician in Protein Biochemistry, Zerial Group role at Human Technopole.
Application closing date: October 19th, 2025.
Human Technopole (HT) is an interdisciplinary life science research institute created and supported by the Italian Government to develop innovative strategies for improving human health. HT comprises five Centres: Neurogenomics, Computational Biology, Structural Biology, Genomics, and Health Data Science. The Centres work together to enable interdisciplinary research and create an open and collaborative environment that will help promote life science research nationally and internationally.
About the lab
The Zerial Group studies the molecular mechanisms of cell and tissue organisation. Its interests range from the assembly and functional characterisation of the endosomal fusion machinery to establishing hepatocyte cell polarity and liver tissue structure and function. The Group uses a unique interdisciplinary approach combining biochemical and biophysical methods with advanced light microscopy, cell biology and computer‑aided three‑dimensional (3D) tissue reconstruction to investigate the organisation and function of the mouse and human liver tissue.
Key tasks and responsibilities

Investigate protein trafficking and compartmentalisation on the endosomal membrane.
Protein purification from different sources.
Design and execution of biochemical and in vitro reconstitution assays.
Use specialised laboratory equipment to perform tests and analyse samples/data.
Support, train, and assist in supervising group members with their work.
Work closely with other technical staff members on general organisation and administrative duties for the organisation of the lab.
Keep detailed, accurate and understandable records of experimental plans and work, and perform data analysis and statistical assessment.
Participate in managing laboratory reagents, equipment, consumables, and stocks.

Job requirements
The candidate should be able to interact with members of an interdisciplinary team of cell biologists, biochemists, computer scientists and clinicians, work in a competitive international environment and possess excellent communication skills.

Bachelor/Master’s degree in biology, biotechnology or a related discipline.
Excellent expertise in molecular and biochemical techniques.
Proficiency in designing and executing biochemical and in vitro reconstitution assays.
At least three years work experience in an academic environment.
Ability to execute complex protocols.
Ability to work independently and re‑prioritise tasks based on emerging needs and requests from other team members.
Good organisational skills and ability to multitask.
Strong problem‑solving skills.
Fluency in English.

Preferred requirements

A background in membrane biology, endocytosis and cell trafficking would be advantageous.
Experience in proteomics would be beneficial.

Organisational and social skills

Good organisational skills and ability to multitask.
Strong problem‑solving skills.
Fluency in English.

Application instructions

CV.
Motivation letter in English relating your track record to the specifics of the call.
Names and contacts of 2 referees.

Why Human Technopole
HT seeks scientific excellence. We recruit the best scientific talents through international, open calls. Our working environment is international, friendly and inclusive. Our scientists work together across disciplines on research topics of biomedical relevance, leveraging synergies between their diverse skill sets and methodological approaches. We believe that highly diverse teams yield the best and most innovative results. We engage in outward‑facing scientific activities to benefit the national and international research community. Training is also at the heart of our activity, with initiatives and opportunities for our staff, including scientific courses, conferences and workshops.
Benefits

Work‑life balance provisions.
Italian language training for foreigners.
Parental leave for up to 1 year and other support for new parents.
Relocation support.

Contract details
Number of positions offered: 1.
Contract offered: CCNL Chimico Farmaceutico, Fixed‑term 3 years - employee level.
Location
The position is based in Milan.
Seniority level
Mid‑Senior level
Employment type
Full‑time
Job function
Research
Industries
Research Services
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