Oncology, Senior Director Clinical Operations Disease Area Lead
Join GSK to lead clinical operations in oncology. This role drives innovation and transforms healthcare on a global scale.
Job Purpose
As the Oncology Senior Director Disease Area Lead at GSK, you will drive the global strategy for clinical operations within your portfolio, ensuring operational excellence, accelerating development timelines, and optimizing delivery to support GSK’s mission of improving health outcomes worldwide.
Key Responsibilities

Lead a high‑performing global team of Clinical Operations Asset Leads and Associate COALs setting the strategic vision and operational direction for delivering the disease area portfolio including Early Phase strategy and delivery.
Contribute to the Business Development strategic input when opportunities are evaluated by providing strategic leadership, due diligence, and building a clinical development plan in preparation for governance.
Lead the Disease Area Matrix Leadership Team by partnering with key Oncology stakeholders to shape the vision and resourcing/delivery strategy to support the clinical portfolio from design through regulatory submission/approvals.
Provide leadership and coaching to team members accountable for the delivery of clinical development programs, ensuring talent development and retention, and fostering a culture of innovation and accountability.
Work with GCO TA head to set the strategic direction for the GCO TA teams, ensuring alignment with GSK’s R&D objectives and overall company strategy.
Identify and integrate best practices across the organization, implementing them to enhance business processes, optimize operational efficiency, and foster continuous improvement.
Act as the single point of accountability for all operational aspects of Oncology, providing strategic oversight and ensuring delivery against key milestones, timelines, and quality standards.
Embed innovative approaches to drive delivery optimization and accelerate development timelines across the life cycle of an asset.
Proactively identify and manage risks associated with clinical program delivery, developing and implementing strategies to mitigate risks and ensure successful execution of trials.
Shape and sustain a culture of excellence, collaboration, accountability, and innovation within the organization, fostering the sharing of best practices and the development of key talent.

Basic Qualifications

Bachelor’s degree in a scientific discipline with knowledge and experience in Oncology drug development at a senior strategic level within Clinical Operations.
Proven line and matrix leadership and ability to navigate, lead and influence within a complex matrix environment.
Experience working independently with senior executives, quickly building personal credibility and assimilating complex business issues or needs.
Experience in leading organization‑wide problem solving and conducting high‑quality strategic analysis, implementing innovative solutions to address complex challenges.

Preferred Qualifications

Advanced degree (Master’s or Doctorate) in a scientific discipline.
Expertise in driving innovative solutions to optimize operational delivery and accelerate development timelines.
High level of personal drive, energy, enthusiasm, and commitment, with proven ability to motivate and inspire teams to achieve exceptional results.
High degree of creativity and innovation in developing new approaches, processes and methodologies.
Highly effective verbal, written, presentation and communications skills, with ability to articulate complex issues and strategies clearly and persuasively.
Strong business acumen with ability to balance strategic vision and operational execution.
Experience collaborating with external stakeholders, including CROs, academia, and patient networks.
Strong influencing and negotiation skills in challenging, ambiguous and rapidly changing environments.

Benefits Summary
Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
EEO Statement
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
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